Step 1: Read the paragraph below. This is written at a postgraduate clinical level: dense, jargon-heavy, and typical of what appears in UpToDate or a clinical guideline.

Source Paragraph – Postgraduate Clinical Level

In patients with newly diagnosed hypertension and an estimated glomerular filtration rate above 60 mL/min/1.73m², first-line pharmacotherapy with an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker is recommended, particularly in the presence of concurrent proteinuria or diabetes mellitus type 2, given their nephroprotective and cardioprotective properties in reducing end-organ damage progression.

Step 2:  Your plain language rewrite

Target: grade 6–8 reading level

Rewrite the paragraph above so that a patient or family member with no medical background could easily understand it. Aim for 2–4 short sentences. Avoid jargon. Use the everyday words list below if helpful.

CDC Everyday words reference

Hypertension: High blood pressure

ACE/ARB inhibitor: A type of blood pressure medicine

Nephroprotective: protects your kidneys

Concurrent: at the same time

Pharmacotherapy: medicine/medication

Proteinuria: protein in your urine

Cardioprotective: protects your heart

End-organ damage: damage to organs like the kidneys or the heart