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Cancer Cachexia Education Initiative
Supported by Pfizer, this flagship initiative aims to improve awareness, recognition, and clinical management of cancer cachexia among healthcare providers across the United States. Cancer cachexia remains significantly under-recognized despite its major impact on survival, treatment tolerance, and quality of life for patients living with cancer. Through this initiative, eHealthyInfo is developing high-quality, evidence-based educational…
Myths to Medicine Podcast
The Myths to Medicine podcast is a global expert-driven educational platform designed to break down common medical myths and translate complex medical science into clear, practical, and patient-centered knowledge. Led by Ashma Baruwal, MPH, the podcast features conversations with health experts from the United States and around the world. The series focuses on bridging the gap between…
Global Research Webinar Series
In collaboration with the American Journal of Patient Health Information, eHealthyInfo is planning a six-month webinar series designed to support medical students, residents, fellows, and early-career researchers interested in clinical and health services research. The webinar curriculum focuses on practical and high-impact research skill development including grant writing fundamentals, large inpatient database research methodologies, and…
Systematic Review, Meta-Analysis, and Evidence Mapping Program
eHealthyInfo is currently coordinating multiple international systematic review and evidence mapping projects in collaboration with researchers from across the world. These projects focus on clinically meaningful topics in medicine and public health, with an emphasis on implementation science, real-world outcomes research, and evidence synthesis that directly supports clinical decision-making. This program reflects eHealthyInfo’s commitment to generating…
bmi and cancer cachexia
BMI and Cancer Cachexia
Role of BMI and BMI-Adjusted Weight Loss in Cancer Cachexia BMI plays an important role in assessing cancer cachexia because it helps us understand how serious a patient’s weight loss really is. The same percentage of weight loss has very different meanings depending on where a patient starts. For example, losing 3% of body…
stages of cancer cachexia
3 Stages of Cancer Cachexia
Pre-Cachexia, Cachexia and Refractory Cachexia Cancer cachexia progresses through three distinct clinical stages, each with increasing severity. 1. Pre-cachexia This is where the earliest signs appear. Patients may have mild, unintentional weight loss, reduced appetite, and changes in metabolism, especially glucose handling. It’s subtle and often missed, but this stage offers the best…
cancer cachexia mechanism
Cancer Cachexia Pathophysiology
Cancer Cachexia WeightLoss Expalined It all starts with the tumor. Tumor cells release several inflammatory cytokines—mainly TNF-alpha, IL-1, IL-6, and IL-8. These cytokines circulate throughout the body and trigger a chain reaction that disrupts normal metabolism. One major target is the skeletal muscle. These cytokines activate pathways that increase proteolysis—meaning the muscle starts breaking down…

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