Irritable Bowel Syndrome (IBS) – Causes, Triggers, Symptoms and Treatment

Irritable Bowel Syndrome (IBS) – Causes, Triggers, Symptoms and Treatment


Key Highlights

  • Irritable Bowel Syndrome(IBS) is one of the most commonly diagnosed gastrointestinal diseases and is seen in 10% to 15% of people in the United States.
  • Symptoms of IBS include recurring abdominal cramping, changes in bowel habits, and variations in stool consistency (diarrhea, constipation, or both).
  • There is no definitive blood or imaging test to diagnose IBS.
  • Understanding and addressing triggers, like certain foods, stress, or lifestyle factors, can significantly impact and alleviate symptoms in individuals with IBS.
  • Behavioral therapies, such as cognitive-behavioral therapy and gut-directed hypnotherapy, can help effectively manage symptoms.

What is Irritable Bowel Syndrome (IBS)?

Irritable bowel syndrome (IBS) is one of the common gastrointestinal disorders that is diagnosed in millions of people worldwide and affects approximately 10-15% of the United States population. It is more common in the Western world, with women being affected twice as often as men, and its symptoms start as early as childhood or adulthood. Although IBS does not result in structural damage to the digestive tract, its impact on individuals’ daily lives can be profound, often leading to missed workdays, reduced social activities, and overall diminished quality of life.

What Are The Causes Of Irritable Bowel Syndrome?

The definite cause of IBS has yet to be fully understood, and it likely involves a complex interplay of various factors. IBS is a functional gastrointestinal disorder, and several factors are believed to contribute to its development. These include:
  • Altered Gut Motility

    The muscles in your gut are responsible for the movement of food with the help of a series of contractions and relaxation. Alterations in the pattern of these movements can lead to changes in bowel habits, such as diarrhea or constipation. These alterations in gut motility are commonly seen in individuals with IBS.

  • Visceral Hypersensitivity

    Recent studies have shown the relation of IBS with the hypersensitivity of the nerves found on the gut wall. This heightened response to normal stimuli can result in the perception of pain or discomfort even with normal bowel function.

  • Microbiota Imbalance

    Alterations in the composition and function of the gut microbiota (microorganisms residing in the digestive tract) have been observed in individuals with IBS. An imbalance in the microbiota may contribute to symptom development.

  • Genetic Factors

    A genetic predisposition to developing IBS may exist. Many individuals with IBS have also been found to have a family history of the condition.

  • Dietary Factors

    Certain foods and dietary patterns can trigger or worsen IBS symptoms. Common triggers include high-fat foods, dairy products, certain carbohydrates, and artificial sweeteners.

  • Psychosocial Factors

    Psychological factors such as stress, anxiety, and depression can influence the onset and exacerbation of IBS symptoms. The connection that exists between your gut and brain plays a significant role in the manifestation of symptoms.

Triggers of Irritable Bowel Syndrome

Triggers for IBS can differ among individuals, and identifying specific triggers is crucial for managing symptoms. Common triggers include:
Triggers for irritable bowel syndrome symptoms
  • Dietary Factors

    Certain foods may trigger IBS symptoms. Common culprits include high-fat foods, spicy foods, caffeine, alcohol, dairy products, and foods high in fermentable carbohydrates (FODMAPs). You can keep a food diary to help identify specific triggers.

  • Stress and Anxiety

    Emotional factors, particularly stress and anxiety, often contribute to IBS symptoms. High stress levels or anxiety can exacerbate abdominal pain and discomfort and alter bowel habits.

  • Hormonal Changes

    Fluctuations in hormones, especially in women during menstruation or menopause, can influence IBS symptoms. Some individuals may experience an increase in symptoms during these hormonal changes.

  • Certain Beverages

    Carbonated beverages, artificial sweeteners, and drinks with high caffeine content can be triggers for some individuals with IBS. You should keep yourself hydrated with water to avoid having flare-ups when consuming these beverages.

  • Smoking

    Smoking has been associated with an increased risk of IBS and can exacerbate symptoms. Quitting smoking may contribute to symptom improvement.

What Are The Types Of Irritable Bowel Syndrome?

IBS is classified into different types based on the predominant bowel habits and symptoms experienced by individuals. The three main types of IBS are:

  • IBS with Diarrhea (IBS-D)

    Individuals with IBS-D experience frequent episodes of diarrhea as a predominant symptom. Other common symptoms may include urgency, a sense of incomplete bowel movements, abdominal pain, and discomfort.

  • IBS with Constipation (IBS-C)

    IBS-C is characterized by infrequent and difficult-to-pass stools, with constipation being the predominant symptom. Individuals with IBS-C may experience abdominal pain, bloating, and a feeling of incomplete evacuation.

  • Mixed-Type IBS (IBS-M)

    This type of IBS involves a combination of both diarrhea and constipation, with alternating periods of each. Individuals with IBS-M may experience a range of symptoms, including abdominal discomfort, bloating, and variations in bowel habits. The alternating nature of diarrhea and constipation can make management challenging, and treatment may focus on addressing specific symptoms.

  • Undefined subtype IBS (IBS-U)

    It is an additional category for individuals whose symptoms do not clearly fit into the other categories.

Irritable Bowel Syndrome Symptoms

The symptoms of IBS often wax and wane, and they may be triggered or worsened by factors such as stress, diet, and hormonal changes. The primary symptoms of IBS include:

irritable bowel syndrome symptoms

  • Abdominal Pain or Discomfort

    It is the most common symptom and is important in establishing the diagnosis. The pain of IBS is typically located in the lower abdomen and may be described as crampy or sharp. These symptoms emerge after eating specific foods, food intake, or emotional stress and are often relieved by bowel movements.

  • Altered Bowel Habits

    In a diarrhea-predominant IBS, you might want to suddenly and immediately want to evacuate your bowels. The diarrhea in IBS occurs during the day. The stool appears loose and watery and may also contain mucus. If you have constipation-predominant IBS, you might have a sensation of incomplete bowel movement. As a result, one might strain unnecessarily. There’s a great relief once the gas or stool is passed.

  • Symptoms unrelated to the intestine

    People with IBS also experience symptoms unrelated to the intestine. Fatigue and disrupted sleep patterns are often reported by individuals with IBS, possibly due to the impact of symptoms on overall well-being and quality of life. There are various emotional factors, such as anxiety and depression, that are also associated with IBS.

  • Other GI symptoms

    Many individuals with IBS report bloating and a sensation of abdominal distension. Some people with IBS may experience a sudden and urgent need to have a bowel movement. This urgency is usually associated with IBS-D. A feeling of incomplete bowel movements is also commonly seen in individuals with IBS. Despite having a bowel movement, there may be a sense that the rectum is not completely empty.

Red Flags for IBS

Certain symptoms should not be overlooked as they can be a part of a grave diagnosis and should not be labeled as a part of IBS without further investigation. These include:

  • Family history of colon cancer
  • Unintentional weight loss
  • Experiencing the symptoms at night
  • Anemia
  • Rectal bleeding

Diagnosis of Irritable Bowel Syndrome

The diagnosis of IBS is typically based on a combination of clinical findings and the
exclusion of other potential gastrointestinal disorders. There isn’t a specific test for
IBS and the process involve a thorough evaluation by a healthcare professional.
The key steps in the diagnosis of IBS include:

irritable bowel syndrome diagnosis

  • Clinical Assessment

    Your doctor, often your primary care physician or a gastroenterologist will conduct a comprehensive clinical assessment. This involves taking a detailed medical history, including the nature and duration of symptoms, their impact on daily life, and any triggering or exacerbating factors.

  • Rome Criteria

    The Rome criteria is widely used by clinicians to diagnose functional gastrointestinal disorders, including IBS. According to these criteria, IBS is diagnosed when symptoms last at least three days per month in the last three months.

  • Exclusion of Other Conditions

    To confirm the diagnosis of IBS, other conditions with similar symptoms are ruled out first. This process may involve laboratory tests, stool tests, imaging studies, and endoscopic procedures to identify or exclude conditions such as inflammatory bowel disease (IBD), celiac disease, and other organic gastrointestinal disorders.

Treatment of Irritable Bowel Syndrome

The treatment of IBS typically involves a multifaceted approach to managing
symptoms and improving the individual’s overall quality of life. The treatment plan
often needs to be personalized based on the specific symptoms and needs of the
patient. Here are common strategies used in the management of IBS:

IBS Treatment

 

1. Dietary Modifications

Some individuals with IBS find relief by following a low-FODMAP diet, which involves restricting certain types of fermentable carbohydrates known as FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols). This kind of diet is more helpful in patients with complaints of abdominal bloating. A dietitian can guide patients in implementing and maintaining this diet. You should limit the intake of dairy products and gluten as lactose intolerance and gluten intolerance is a common entity among people with IBS.

2. Fiber Supplementation

Soluble fiber in food like oats and psyllium may help regulate bowel movements and alleviate symptoms in individuals with constipation-type IBS. However, the introduction of fiber should be gradual to avoid worsening symptoms.

3. Lifestyle modification

Several activities are found to be helpful in the management
of IBS, including:

  • Regular exercise
  • Stress management techniques (e.g., mindfulness, yoga)
  • Maintaining a consistent sleep

4. Best IBS Medicine

  • Antispasmodic Medications: These medications, such as hyoscyamine
    and dicyclomine can help relieve abdominal pain and cramping by
    relaxing the gastrointestinal tract muscles. These medications are
    prescribed mostly for people with diarrhea as they are more prone to
    undergo spasm. However, side effects like constipation, dry mouth, and
    blurred vision must be monitored closely while on these medications.
  • Antidiarrheal Medications: For individuals with IBS-D, loperamide may
    be recommended to control diarrhea. Medications like cholestyramine,
    which binds bile acid, can be prescribed to help control diarrhea.
  • Laxatives: People with IBS-C may be prescribed laxatives if the fiber
    supplement alone does not help. Your doctor may prescribe mild laxatives
    like lubiprostone and Linaclotide to alleviate constipation.
  • Low-Dose Antidepressants: Tricyclic antidepressants and selective
    serotonin reuptake inhibitors (SSRIs) in low doses may help manage pain,
    discomfort, and other symptoms.

5. Counseling and Psychotherapy

Behavioral therapies, such as cognitive-behavioral therapy (CBT) and gut-directed hypnotherapy, have shown effectiveness in managing symptoms, especially in individuals with IBS, where stress and psychological factors play a significant role.

Questions To Ask Your Doctor About IBS

  1. Should I talk to a nutritionist to manage my IBS?
  2. Are my children at risk of having IBS?
  3. Is there an increased risk of having any kind of cancer if I have IBS?
  4. What can I do to increase the symptom-free period?
  5. How would I know what type of IBS I have?

References

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